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Bone damage and bone repair options

The bony skeleton is an active living organ surviving on its own blood vessels. It has two primary functions: structure and storage. Structurally, bones protect your other organs. They create a framework for muscles and tendons that allow you to move. As a storehouse, bones stockpile essential minerals. These minerals (mostly calcium) make it possible for the heart to beat; muscles to contract; nerves to conduct impulses; and other bodily processes.

Think of bone as a bank account where you “deposit” and “withdraw” bone tissue. During childhood and the teenage years, new bone is added to the skeleton faster than old bone is removed. As a result, bones become larger, heavier, and denser.

After age 20, bone “withdrawals” can begin to exceed “deposits.” due to lack of calcium, vitamin D, exercise , or injury, genetics, tobacco and excessive alcohol use. However, too many withdrawals can lead to damage and bones will break with only little trauma leading to complete disability and necrosis ( bone death). The only solution is total hip replacement .

Although it can happen in any bone, osteonecrosis most commonly affects the bone extending from the knee joint to the hip joint, upper arm bone, knees, shoulders, and ankles.

In the course of avascular necrosis, however, the healing process is usually ineffective and the bone tissues break down faster than the body can repair them. If left untreated, the disease progresses, the bone collapses, and the joint surface breaks down, leading to pain and arthritis and permanent immobility for life.

Current treatments of Bone Regeneration

A. Medications. Nonsteroidal anti-inflammatory drugs (NSAIDs) are often prescribed to reduce pain but this is temporary solution

B. Core decompression. This surgical procedure drills holes in the bone, which reduces pressure within and increases blood flow to the bone preventing decay. However, it has very low potential for regeneration of bone.

C. Osteotomy. This treatment involves reshaping the bone to reduce stress on the affected area. Recovery is with limited activity level, with continued knee pain and discomfort.

D. Bone graft. This is the transplantation of healthy bone from another part of the body to increase the blood supply to the affected area.

E. Joint replacement :-the pain is gone (or very minimal) but activities are limited.

Years of clinical research in developing a wide range of biological technologies using biological substances with a goal of fostering regeneration and faster healing for patients suffering from bone, cartilage defects is what we called “ÖRTHOBIOLOGICS”.

Bone Cell therapy is one of the key Orthobiologics procedure which regrows damaged area of a joint through the implantation of one’s own bone marrow cells. It has achieved excellent long term results, both in terms of bone loss and repair and helping patients returning to previous activity levels.